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A piggyBac-based TANGO GFP assay for high throughput screening of GPCR ligands in live cells

BACKGROUND: GPCRs are considered essential for various physiological processes and have been the most productive drug targets. Therefore, development of the methods of GPCR ligands screening is a high priority for pharmaceutical industries and research institutions. METHODS: We developed a potential...

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Detalles Bibliográficos
Autores principales: Li, Fei, Jiang, Xi, Luo, Ling-Ling, Xu, Yue-Ming, Huang, Xing-Xu, Huang, Cheng, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533772/
https://www.ncbi.nlm.nih.gov/pubmed/31122241
http://dx.doi.org/10.1186/s12964-019-0359-x