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Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region

The killer-cell immunoglobulin-like receptor (KIR) region comprises a fast-evolving family of genes that encode receptors for natural killer (NK) cells and have crucial role in host defense. Evolution of KIR was examined in the context of the human genome. Gene-content diversity and single nucleotid...

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Detalles Bibliográficos
Autores principales: Augusto, Danillo G., Norman, Paul J., Dandekar, Ravi, Hollenbach, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533848/
https://www.ncbi.nlm.nih.gov/pubmed/31156615
http://dx.doi.org/10.3389/fimmu.2019.00989