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T(H)1-Polarized T(FH) Cells Delay Naturally-Acquired Immunity to Malaria

Humoral immunity is a critical effector arm for protection against malaria but develops only slowly after repeated infections. T cell-mediated regulatory dynamics affect the development of antibody responses to Plasmodium parasites. Here, we hypothesize that T follicular helper cell (T(FH)) polariza...

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Detalles Bibliográficos
Autores principales: Yap, Xi Zen, Hustin, Lucie S. P., Sauerwein, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533880/
https://www.ncbi.nlm.nih.gov/pubmed/31156642
http://dx.doi.org/10.3389/fimmu.2019.01096