Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) loci and their associated (cas) genes encode an adaptive immune system that protects prokaryotes from viral(1) and plasmid(2) invaders. Upon viral (phage) infection, a small fraction of the prokaryotic cells are able to integrate a s...

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Detalles Bibliográficos
Autores principales: Varble, Andrew, Meaden, Sean, Barrangou, Rodolphe, Westra, Edze R., Marraffini, Luciano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533911/
https://www.ncbi.nlm.nih.gov/pubmed/30886355
http://dx.doi.org/10.1038/s41564-019-0400-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533911/
https://www.ncbi.nlm.nih.gov/pubmed/30886355
http://dx.doi.org/10.1038/s41564-019-0400-2

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