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Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) loci and their associated (cas) genes encode an adaptive immune system that protects prokaryotes from viral(1) and plasmid(2) invaders. Upon viral (phage) infection, a small fraction of the prokaryotic cells are able to integrate a s...
Autores principales: | Varble, Andrew, Meaden, Sean, Barrangou, Rodolphe, Westra, Edze R., Marraffini, Luciano A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533911/ https://www.ncbi.nlm.nih.gov/pubmed/30886355 http://dx.doi.org/10.1038/s41564-019-0400-2 |
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