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The relationship between proton pump inhibitors and renal disease

Proton pump inhibitors (PPIs) bind to enzyme H(+)/K(+)-ATPase and inhibit its activity in the stomach, thus decreasing the secretion of gastric acid. PPIs may trigger acute interstitial nephritis, a potentially severe adverse event commonly associated with acute kidney injury. Studies have found tha...

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Detalles Bibliográficos
Autores principales: Morschel, Carine Franco, Mafra, Denise, Eduardo, José Carlos Carraro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533960/
https://www.ncbi.nlm.nih.gov/pubmed/30010692
http://dx.doi.org/10.1590/2175-8239-JBN-2018-0021