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The relationship between proton pump inhibitors and renal disease
Proton pump inhibitors (PPIs) bind to enzyme H(+)/K(+)-ATPase and inhibit its activity in the stomach, thus decreasing the secretion of gastric acid. PPIs may trigger acute interstitial nephritis, a potentially severe adverse event commonly associated with acute kidney injury. Studies have found tha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Nefrologia
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533960/ https://www.ncbi.nlm.nih.gov/pubmed/30010692 http://dx.doi.org/10.1590/2175-8239-JBN-2018-0021 |