Synthesis of modified 1,5-imino-d-xylitols as ligands for lysosomal β-glucocerebrosidase

ABSTRACT: Modified 1,5-dideoxy-1,5-imino-d-xylitol analogues with different substitution patterns involving position C-1 and/or the ring nitrogen were prepared, which were designed to serve as precursors for the preparation of iminoxylitol-based ligands and tools for the elucidation and modulation o...

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Detalles Bibliográficos
Autores principales: Zoidl, Manuel, Wolfsgruber, Andreas, Schalli, Michael, Nasseri, Seyed A., Weber, Patrick, Stütz, Arnold E., Withers, Stephen G., Wrodnigg, Tanja M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534063/
https://www.ncbi.nlm.nih.gov/pubmed/31178604
http://dx.doi.org/10.1007/s00706-019-02427-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534063/
https://www.ncbi.nlm.nih.gov/pubmed/31178604
http://dx.doi.org/10.1007/s00706-019-02427-1

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