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Synthesis of modified 1,5-imino-d-xylitols as ligands for lysosomal β-glucocerebrosidase
ABSTRACT: Modified 1,5-dideoxy-1,5-imino-d-xylitol analogues with different substitution patterns involving position C-1 and/or the ring nitrogen were prepared, which were designed to serve as precursors for the preparation of iminoxylitol-based ligands and tools for the elucidation and modulation o...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534063/ https://www.ncbi.nlm.nih.gov/pubmed/31178604 http://dx.doi.org/10.1007/s00706-019-02427-1 |