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APC/C: current understanding and future perspectives

The separation of sister chromatids at anaphase, which is regulated by an E3 ubiquitin ligase called the anaphase-promoting complex/cyclosome (APC/C), is arguably the most important irrevocable event during the cell cycle. The APC/C and cyclin-dependent kinase 1 (Cdk1) are just two of the many signi...

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Detalles Bibliográficos
Autor principal: Yamano, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534075/
https://www.ncbi.nlm.nih.gov/pubmed/31164978
http://dx.doi.org/10.12688/f1000research.18582.1