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Synthesis and biological evaluation of 3–(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer’s disease agents

The work is focused on the design of drugs that prevent and treat Alzheimer’s disease (AD) and its complications. A series of 3–(4-aminophenyl)-coumarin derivatives designed, synthesised, fully characterised and evaluated in vitro/vivo. The biological assay experiments showed that some compounds dis...

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Detalles Bibliográficos
Autores principales: Hu, Yu-Heng, Yang, Jie, Zhang, Yun, Liu, Ke-Chun, Liu, Teng, Sun, Jie, Wang, Xiao-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534212/
https://www.ncbi.nlm.nih.gov/pubmed/31117844
http://dx.doi.org/10.1080/14756366.2019.1615484