Cargando…

Synthesis and biological evaluation of 3–(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer’s disease agents

The work is focused on the design of drugs that prevent and treat Alzheimer’s disease (AD) and its complications. A series of 3–(4-aminophenyl)-coumarin derivatives designed, synthesised, fully characterised and evaluated in vitro/vivo. The biological assay experiments showed that some compounds dis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Yu-Heng, Yang, Jie, Zhang, Yun, Liu, Ke-Chun, Liu, Teng, Sun, Jie, Wang, Xiao-Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534212/ https://www.ncbi.nlm.nih.gov/pubmed/31117844 http://dx.doi.org/10.1080/14756366.2019.1615484

Ejemplares similares

Synthesis and anti-rheumatoid arthritis activities of 3-(4-aminophenyl)-coumarin derivatives
por: Miao, Yuhang, et al.
Publicado: (2021)

Design, Synthesis and Preliminary Biological Evaluation of Benzylsulfone Coumarin Derivatives as Anti-Cancer Agents
por: Wang, Tao, et al.
Publicado: (2019)

Synthesis and biological evaluation of 3-arylbenzofuranone derivatives as potential anti-Alzheimer’s disease agents
por: Yang, Jie, et al.
Publicado: (2020)

Synthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer's disease agents
por: Yang, Jie, et al.
Publicado: (2019)

Biological Activity of Coumarin Derivatives as Anti-Leishmanial Agents
por: Mandlik, Vineetha, et al.
Publicado: (2016)

Design, Synthesis and Biological Evaluation of Novel 4-Substituted Coumarin Derivatives as Antitumor Agents
por: An, Ran, et al.
Publicado: (2018)

Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer’s disease agents
por: Yun, Yinling, et al.
Publicado: (2021)

Synthesis and biological evaluation of 3-arylcoumarin derivatives as potential anti-diabetic agents
por: Hu, Yuheng, et al.
Publicado: (2018)

Synthesis and application of coumarin fluorescence probes
por: Sun, Xiao-ya, et al.
Publicado: (2020)

Design, Synthesis, and Mechanism of Dihydroartemisinin–Coumarin Hybrids as Potential Anti-Neuroinflammatory Agents
por: Yu, Haonan, et al.
Publicado: (2019)

Synthesis and Evaluation of New Coumarin Derivatives as Antioxidant, Antimicrobial, and Anti-Inflammatory Agents
por: Alshibl, Hanan M., et al.
Publicado: (2020)

Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents
por: Bruna-Haupt, Ezequiel F., et al.
Publicado: (2023)

Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents
por: Mzezewa, Sheunopa C., et al.
Publicado: (2021)

Synthesis and application of aminophenyl-s-triazine derivatives as potential flame retardants in the modification of epoxy resins
por: Wu, Haiyang, et al.
Publicado: (2018)

Novel Coumarin 7-Carboxamide/Sulfonamide Derivatives as Potential Fungicidal Agents: Design, Synthesis, and Biological Evaluation
por: Zhang, Shu-Guang, et al.
Publicado: (2022)

The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents
por: Shang, Hai, et al.
Publicado: (2022)

Synthesis and Biological Evaluation of Some New Coumarin Derivatives
por: Al-Haiza, M.A., et al.
Publicado: (2003)

Research progress of coumarins and their derivatives in the treatment of diabetes
por: Pan, Yinbo, et al.
Publicado: (2022)

Synthesis and Antimicrobial Studies of Coumarin-Substituted Pyrazole Derivatives as Potent Anti-Staphylococcus aureus Agents
por: Alnufaie, Rawan, et al.
Publicado: (2020)

Design, synthesis, and evaluation of novel coumarin-dithiocarbamate derivatives (IDs) as anti-colorectal cancer agents
por: Zhu, Heping, et al.
Publicado: (2021)

Synthesis and biological evaluation of coumarin-quinone hybrids as multifunctional bioactive agents
por: Pangal, Anees, et al.
Publicado: (2022)

Synthesis and biological evaluation of stilbene derivatives coupled to NO donors as potential antidiabetic agents
por: Wang, Bing, et al.
Publicado: (2018)

Synthesis and Biological Evaluation of Harmirins, Novel Harmine–Coumarin Hybrids as Potential Anticancer Agents
por: Pavić, Kristina, et al.
Publicado: (2021)

Synthesis and Biological Activity Evaluation of Coumarin-3-Carboxamide Derivatives
por: Phutdhawong, Weerachai, et al.
Publicado: (2021)

Three-Component Synthesis of Some New Coumarin Derivatives as Anticancer Agents
por: Alshabanah, Latifah A., et al.
Publicado: (2022)

Synthesis of Coumarin and Homoisoflavonoid Derivatives and Analogs: The Search for New Antifungal Agents
por: Ferreira, Alana R., et al.
Publicado: (2022)

Synthesis, Spectroscopy, and Computational Analysis of Photoluminescent Bis(aminophenyl)-Substituted Thiophene Derivatives
por: Lumpi, Daniel, et al.
Publicado: (2013)

Synthesis and Biological Evaluation of New Ligustrazine Derivatives as Anti-Tumor Agents
por: Wang, Penglong, et al.
Publicado: (2012)

Novel coumarin–benzimidazole derivatives as antioxidants and safer anti-inflammatory agents
por: Arora, Radha Krishan, et al.
Publicado: (2014)

Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, in vitro biological evaluation, and QSAR studies
por: Sabt, Ahmed, et al.
Publicado: (2018)

Design, synthesis, in vitro, and in silico biological evaluations of coumarin-indole hybrids as new anti-α-glucosidase agents
por: Niri, Davood Rezapour, et al.
Publicado: (2022)

Design, Synthesis and Biological Evaluation of Neocryptolepine Derivatives as Potential Anti-Gastric Cancer Agents
por: Ma, Yunhao, et al.
Publicado: (2022)

Biological synthesis of coumarins in Escherichia coli
por: Yang, So-Mi, et al.
Publicado: (2015)

Synthesis and biological evaluation of esculetin derivatives as potential anti-HBV agents
por: Ye, Zhen, et al.
Publicado: (2023)

Coumarin Derivative N6 as a Novel anti-hantavirus Infection Agent Targeting AKT
por: Li, Zhoupeng, et al.
Publicado: (2021)

2-(4-Aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity.
por: Bradshaw, T. D., et al.
Publicado: (1998)

Synthesis and Biological Evaluation of Novel Acenaphthene Derivatives as Potential Antitumor Agents
por: Xie, Yong-Mei, et al.
Publicado: (2011)

Synthesis 1-Acyl-3-(2'-aminophenyl) thioureas as Anti-Intestinal Nematode Prodrugs
por: Duan, Li-Ping, et al.
Publicado: (2010)

Natural product-inspired synthesis of coumarin–chalcone hybrids as potential anti-breast cancer agents
por: Alhakamy, Nabil A., et al.
Publicado: (2023)

Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition
por: Kamel, Nahla N., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_in33sf92s6bunglsp84srb14a1