Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells

Chalcones are valuable structures for drug discovery due to their broad bioactivity spectrum. In this study, we evaluated 20 synthetic chalcones against estrogen-receptor-positive breast cancer cells (MCF-7 line) and triple-negative breast cancer (TNBC) cells (MDA-MB-231 line). Antiproliferative scr...

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Detalles Bibliográficos
Autores principales: dos Santos, Mariana Bastos, Bertholin Anselmo, Daiane, de Oliveira, Jéssica Gisleine, Jardim-Perassi, Bruna V., Alves Monteiro, Diego, Silva, Gabriel, Gomes, Eleni, Lucia Fachin, Ana, Marins, Mozart, de Campos Zuccari, Débora Aparecida Pires, Octavio Regasini, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534249/
https://www.ncbi.nlm.nih.gov/pubmed/31117836
http://dx.doi.org/10.1080/14756366.2019.1615485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534249/
https://www.ncbi.nlm.nih.gov/pubmed/31117836
http://dx.doi.org/10.1080/14756366.2019.1615485

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