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Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative

3-Methylpentyl(4-sulphamoylphenyl)carbamate (MSPC) came as the most potent compound out of a new series of carbamates composed of phenyl-ethanol or branched aliphatic alcohols, and 4-benzenesulphonamide-carbamic acid. In this study, the anticonvulsant activity and pharmacokinetics (PKs) of MSPC-two...

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Detalles Bibliográficos
Autores principales: Bibi, David, Shusterman, Bella, Nocentini, Alessio, Supuran, Claudiu T., Bialer, Meir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534253/
https://www.ncbi.nlm.nih.gov/pubmed/31124389
http://dx.doi.org/10.1080/14756366.2019.1612887