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Sortase-click strategy for defined protein conjugation on a heptavalent cyclodextrin scaffold

Multivalent proteins or protein dendrimers are useful for clinical and biotechnological applications. However, assembly of chemically defined protein dendrimers is a challenging endeavor. In the past, majority of protein dendrimers have been developed on branched lysine scaffolds and are usually lim...

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Detalles Bibliográficos
Autores principales: Singh, Shikha, Gupta, Kanchan, Shukla, Shagun, Sampathkumar, Srinivasa-Gopalan, Roy, Rajendra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534326/
https://www.ncbi.nlm.nih.gov/pubmed/31125361
http://dx.doi.org/10.1371/journal.pone.0217369