Double Nitroxide Labeling by Copper-Catalyzed Azide–Alkyne Cycloadditions with Noncanonical Amino Acids for Electron Paramagnetic Resonance Spectroscopy

[Image: see text] Electron paramagnetic resonance spectroscopy in combination with site-directed spin labeling (SDSL) is an important tool to obtain long-range distance restraints for protein structural research. We here study a variety of azide- and alkyne-bearing noncanonical amino acids (ncAA) in...

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Detalles Bibliográficos
Autores principales: Widder, Pia, Berner, Frederic, Summerer, Daniel, Drescher, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534342/
https://www.ncbi.nlm.nih.gov/pubmed/30998314
http://dx.doi.org/10.1021/acschembio.8b01111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534342/
https://www.ncbi.nlm.nih.gov/pubmed/30998314
http://dx.doi.org/10.1021/acschembio.8b01111

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