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Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells

Biliary esophageal reflux at acidic pH is considered a risk factor in laryngopharyngeal cancer. We previously showed the key role NF-κB in mediating acidic bile-induced pre-neoplastic events in hypopharyngeal cells, and that co-administration of specific NF-κB inhibitor, BAY 11-7082, together with a...

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Detalles Bibliográficos
Autores principales: Doukas, Panagiotis G., Vageli, Dimitra P., Doukas, Sotirios G., Sasaki, Clarence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534360/
https://www.ncbi.nlm.nih.gov/pubmed/31164956
http://dx.doi.org/10.18632/oncotarget.26917