Cargando…
Temporal characteristics of NF-κB inhibition in blocking bile-induced oncogenic molecular events in hypopharyngeal cells
Biliary esophageal reflux at acidic pH is considered a risk factor in laryngopharyngeal cancer. We previously showed the key role NF-κB in mediating acidic bile-induced pre-neoplastic events in hypopharyngeal cells, and that co-administration of specific NF-κB inhibitor, BAY 11-7082, together with a...
Autores principales: | Doukas, Panagiotis G., Vageli, Dimitra P., Doukas, Sotirios G., Sasaki, Clarence T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534360/ https://www.ncbi.nlm.nih.gov/pubmed/31164956 http://dx.doi.org/10.18632/oncotarget.26917 |
Ejemplares similares
-
Inhibition of NF-κB prevents the acidic bile-induced oncogenic mRNA phenotype, in human hypopharyngeal cells
por: Vageli, Dimitra P., et al.
Publicado: (2017) -
The temporal effects of topical NF-κB inhibition, in the in vivo prevention of bile-related oncogenic mRNA and miRNA phenotypes in murine hypopharyngeal mucosa: a preclinical model
por: Vageli, Dimitra P., et al.
Publicado: (2020) -
Curcumin prevents the bile reflux‐induced NF‐κB‐related mRNA oncogenic phenotype, in human hypopharyngeal cells
por: Vageli, Dimitra P., et al.
Publicado: (2018) -
Bile reflux and hypopharyngeal cancer
por: Vageli, Dimitra P., et al.
Publicado: (2021) -
Weakly Acidic Bile Is a Risk Factor for Hypopharyngeal Carcinogenesis Evidenced by DNA Damage, Antiapoptotic Function, and Premalignant Dysplastic Lesions In Vivo
por: Sasaki, Clarence T., et al.
Publicado: (2021)