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A DNA telomerase vaccine for canine cancer immunotherapy

Telomerase reverse transcriptase (TERT) is highly expressed in more than 90% of canine cancer cells and low to absent in normal cells. Given that immune tolerance to telomerase is easily broken both naturally and experimentally, telomerase is an attractive tumor associated antigen for cancer immunot...

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Detalles Bibliográficos
Autores principales: Thalmensi, Jessie, Pliquet, Elodie, Liard, Christelle, Chamel, Gabriel, Kreuz, Christine, Bestetti, Thomas, Escande, Marie, Kostrzak, Anna, Pailhes-Jimenez, Anne-Sophie, Bourges, Emmanuèle, Julithe, Marion, Bourre, Ludovic, Keravel, Olivier, Clayette, Pascal, Huet, Thierry, Wain-Hobson, Simon, Langlade-Demoyen, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534364/
https://www.ncbi.nlm.nih.gov/pubmed/31164958
http://dx.doi.org/10.18632/oncotarget.26927