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Targeting IL-6 receptor reduces IgM levels and tumor growth in Waldenström macroglobulinemia

The tumor microenvironment (TME) plays an important role in cancer cell biology and is implicated in resistance to therapy. In Waldenström macroglobulinemia (WM), a subtype of Non-Hodgkin lymphoma, the TME modulates WM biology by secreting cytokines that promote the malignant phenotype. In previous...

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Detalles Bibliográficos
Autores principales: Han, Weiguo, Matissek, Stephan J., Jackson, David A., Sklavanitis, Brandon, Elsawa, Sherine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534366/
https://www.ncbi.nlm.nih.gov/pubmed/31164961
http://dx.doi.org/10.18632/oncotarget.26946