Wnt Signaling Mediates the Aging-Induced Differentiation Impairment of Intestinal Stem Cells

Stem cell aging underlies aging-associated disorders, such as steeply increased incidences of tumors and impaired regeneration capacity upon stress. However, whether and how the intestinal stem cells age remains largely unknown. Here we show that intestinal stem cells derived from 24-month-old mice...

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Detalles Bibliográficos
Autores principales: Cui, Hui, Tang, Duozhuang, Garside, George B., Zeng, Ting, Wang, Yiting, Tao, Zhendong, Zhang, Liu, Tao, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534527/
https://www.ncbi.nlm.nih.gov/pubmed/30790135
http://dx.doi.org/10.1007/s12015-019-09880-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534527/
https://www.ncbi.nlm.nih.gov/pubmed/30790135
http://dx.doi.org/10.1007/s12015-019-09880-9

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