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Mathematical modelling of cell migration: stiffness dependent jump rates result in durotaxis
Durotaxis, the phenomena where cells migrate up a gradient in substrate stiffness, remains poorly understood. It has been proposed that durotaxis results from the reinforcement of focal adhesions on stiff substrates. In this paper we formulate a mathematical model of single cell migration on elastic...
Autores principales: | Malik, Adam A., Gerlee, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534528/ https://www.ncbi.nlm.nih.gov/pubmed/30972438 http://dx.doi.org/10.1007/s00285-019-01344-5 |
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