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Schistosoma mansoni treatment reduces HIV entry into cervical CD4+ T cells and induces IFN-I pathways

Schistosoma mansoni (Sm) infection has been linked with an increased risk of HIV acquisition in women. Therefore, defining the mechanism(s) by which Sm alters HIV susceptibility might lead to new HIV prevention strategies. Here, we analyze the impact of standard Sm therapy in HIV-uninfected Sm+ Ugan...

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Detalles Bibliográficos
Autores principales: Yegorov, Sergey, Joag, Vineet, Galiwango, Ronald M., Good, Sara V., Mpendo, Juliet, Tannich, Egbert, Boggild, Andrea K., Kiwanuka, Noah, Bagaya, Bernard S., Kaul, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534541/
https://www.ncbi.nlm.nih.gov/pubmed/31127086
http://dx.doi.org/10.1038/s41467-019-09900-9