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qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing
DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage and frequently cause genome instability. Sequencing-based methods for mapping DSBs have been developed but they allow measurement only of relative frequencies of DSBs between loci, which limits our understanding of the phy...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534554/ https://www.ncbi.nlm.nih.gov/pubmed/31127121 http://dx.doi.org/10.1038/s41467-019-10332-8 |