Cargando…

qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing

DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage and frequently cause genome instability. Sequencing-based methods for mapping DSBs have been developed but they allow measurement only of relative frequencies of DSBs between loci, which limits our understanding of the phy...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yingjie, Biernacka, Anna, Pardo, Benjamin, Dojer, Norbert, Forey, Romain, Skrzypczak, Magdalena, Fongang, Bernard, Nde, Jules, Yousefi, Razie, Pasero, Philippe, Ginalski, Krzysztof, Rowicka, Maga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534554/
https://www.ncbi.nlm.nih.gov/pubmed/31127121
http://dx.doi.org/10.1038/s41467-019-10332-8