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qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing

DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage and frequently cause genome instability. Sequencing-based methods for mapping DSBs have been developed but they allow measurement only of relative frequencies of DSBs between loci, which limits our understanding of the phy...

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Detalles Bibliográficos
Autores principales:	Zhu, Yingjie, Biernacka, Anna, Pardo, Benjamin, Dojer, Norbert, Forey, Romain, Skrzypczak, Magdalena, Fongang, Bernard, Nde, Jules, Yousefi, Razie, Pasero, Philippe, Ginalski, Krzysztof, Rowicka, Maga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534554/ https://www.ncbi.nlm.nih.gov/pubmed/31127121 http://dx.doi.org/10.1038/s41467-019-10332-8

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