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Alzheimer’s disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

Mild-cognitive impairment (MCI) occurs in up to one-fifth of individuals over the age of 65, with approximately a third of MCI individuals converting to dementia in later life. There is a growing necessity for early identification for those at risk of dementia as pathological processes begin decades...

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Detalles Bibliográficos
Autores principales: Chaudhury, Sultan, Brookes, Keeley J., Patel, Tulsi, Fallows, Abigail, Guetta-Baranes, Tamar, Turton, James C., Guerreiro, Rita, Bras, Jose, Hardy, John, Francis, Paul T., Croucher, Rebecca, Holmes, Clive, Morgan, Kevin, Thomas, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534556/
https://www.ncbi.nlm.nih.gov/pubmed/31127079
http://dx.doi.org/10.1038/s41398-019-0485-7