The antioxidant and DNA-repair enzyme apurinic/apyrimidinic endonuclease 1 limits the development of tubulointerstitial fibrosis partly by modulating the immune system

Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein that controls the cellular response to oxidative stress and possesses DNA-repair functions. It has important roles in the progression and outcomes of various diseases; however, its function and therapeutic prospects with respec...

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Detalles Bibliográficos
Autores principales: Maruyama, Keisuke, Nakagawa, Naoki, Aonuma, Tatsuya, Saito, Yukihiro, Hayasaka, Taiki, Kano, Kohei, Horiuchi, Kiwamu, Takehara, Naofumi, Kawabe, Jun-ichi, Hasebe, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534557/
https://www.ncbi.nlm.nih.gov/pubmed/31127150
http://dx.doi.org/10.1038/s41598-019-44241-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534557/
https://www.ncbi.nlm.nih.gov/pubmed/31127150
http://dx.doi.org/10.1038/s41598-019-44241-z

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