Rapamycin modulates tissue aging and lifespan independently of the gut microbiota in Drosophila

The FDA approved drug rapamycin can prolong lifespan in diverse species and delay the onset of age-related disease in mammals. However, a number of fundamental questions remain unanswered regarding the mechanisms by which rapamycin modulates age-related pathophysiology and lifespan. Alterations in t...

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Detalles Bibliográficos
Autores principales: Schinaman, Joseph M., Rana, Anil, Ja, William W., Clark, Rebecca I., Walker, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534571/
https://www.ncbi.nlm.nih.gov/pubmed/31127145
http://dx.doi.org/10.1038/s41598-019-44106-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534571/
https://www.ncbi.nlm.nih.gov/pubmed/31127145
http://dx.doi.org/10.1038/s41598-019-44106-5

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