The cell-wide web coordinates cellular processes by directing site-specific Ca(2+) flux across cytoplasmic nanocourses

Ca(2+) coordinates diverse cellular processes, yet how function-specific signals arise is enigmatic. We describe a cell-wide network of distinct cytoplasmic nanocourses with the nucleus at its centre, demarcated by sarcoplasmic reticulum (SR) junctions (≤400 nm across) that restrict Ca(2+) diffusion...

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Detalles Bibliográficos
Autores principales: Duan, Jingxian, Navarro-Dorado, Jorge, Clark, Jill H., Kinnear, Nicholas P., Meinke, Peter, Schirmer, Eric C., Evans, A. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534574/
https://www.ncbi.nlm.nih.gov/pubmed/31127110
http://dx.doi.org/10.1038/s41467-019-10055-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534574/
https://www.ncbi.nlm.nih.gov/pubmed/31127110
http://dx.doi.org/10.1038/s41467-019-10055-w

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