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The cell-wide web coordinates cellular processes by directing site-specific Ca(2+) flux across cytoplasmic nanocourses
Ca(2+) coordinates diverse cellular processes, yet how function-specific signals arise is enigmatic. We describe a cell-wide network of distinct cytoplasmic nanocourses with the nucleus at its centre, demarcated by sarcoplasmic reticulum (SR) junctions (≤400 nm across) that restrict Ca(2+) diffusion...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534574/ https://www.ncbi.nlm.nih.gov/pubmed/31127110 http://dx.doi.org/10.1038/s41467-019-10055-w |