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Stress-induced tunneling nanotubes support treatment adaptation in prostate cancer

Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define roles for TNTs in stress adaptation and treatment resistance in prostate cancer (PCa). Androgen receptor (AR) blockade and metabolic stress induce TNTs, but not in norma...

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Detalles Bibliográficos
Autores principales: Kretschmer, Alexander, Zhang, Fan, Somasekharan, Syam Prakash, Tse, Charan, Leachman, Lauren, Gleave, Anna, Li, Brian, Asmaro, Ivan, Huang, Teresa, Kotula, Leszek, Sorensen, Poul H., Gleave, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534589/
https://www.ncbi.nlm.nih.gov/pubmed/31127190
http://dx.doi.org/10.1038/s41598-019-44346-5