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Stress-induced tunneling nanotubes support treatment adaptation in prostate cancer
Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define roles for TNTs in stress adaptation and treatment resistance in prostate cancer (PCa). Androgen receptor (AR) blockade and metabolic stress induce TNTs, but not in norma...
Autores principales: | Kretschmer, Alexander, Zhang, Fan, Somasekharan, Syam Prakash, Tse, Charan, Leachman, Lauren, Gleave, Anna, Li, Brian, Asmaro, Ivan, Huang, Teresa, Kotula, Leszek, Sorensen, Poul H., Gleave, Martin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534589/ https://www.ncbi.nlm.nih.gov/pubmed/31127190 http://dx.doi.org/10.1038/s41598-019-44346-5 |
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