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Human skin equivalents cultured under hypoxia display enhanced epidermal morphogenesis and lipid barrier formation

Human skin equivalents (HSEs) are three-dimensional cell models mimicking characteristics of native human skin (NHS) in many aspects. However, a limitation of HSEs is the altered in vitro morphogenesis and barrier formation. Differences between in vitro and in vivo skin could have been induced by su...

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Detalles Bibliográficos
Autores principales: Mieremet, Arnout, Vázquez García, Adela, Boiten, Walter, van Dijk, Rianne, Gooris, Gert, Bouwstra, Joke A., El Ghalbzouri, Abdoelwaheb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534609/
https://www.ncbi.nlm.nih.gov/pubmed/31127151
http://dx.doi.org/10.1038/s41598-019-44204-4