E4orf1 protein reduces the need for endogenous insulin

BACKGROUND: E4orf1 protein derived from adenovirus-36 reduces glucose excursion in mice, and lowers endogenous insulin response, suggesting a reduced need for insulin. We tested if the E4orf1-mediated lowering of insulin response is due to increased tissue sensitivity to insulin, reduced ability to...

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Detalles Bibliográficos
Autores principales: Peddibhotla, Swetha, Hegde, Vijay, Akheruzzaman, Md, Dhurandhar, Nikhil V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534626/
https://www.ncbi.nlm.nih.gov/pubmed/31127081
http://dx.doi.org/10.1038/s41387-019-0085-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534626/
https://www.ncbi.nlm.nih.gov/pubmed/31127081
http://dx.doi.org/10.1038/s41387-019-0085-x

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