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E4orf1 protein reduces the need for endogenous insulin
BACKGROUND: E4orf1 protein derived from adenovirus-36 reduces glucose excursion in mice, and lowers endogenous insulin response, suggesting a reduced need for insulin. We tested if the E4orf1-mediated lowering of insulin response is due to increased tissue sensitivity to insulin, reduced ability to...
Autores principales: | Peddibhotla, Swetha, Hegde, Vijay, Akheruzzaman, Md, Dhurandhar, Nikhil V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534626/ https://www.ncbi.nlm.nih.gov/pubmed/31127081 http://dx.doi.org/10.1038/s41387-019-0085-x |
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