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Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification
Chromatin looping allows enhancer-bound regulatory factors to influence transcription. Large domains, referred to as topologically associated domains, participate in genome organization. However, the mechanisms underlining interactions within these domains, which control gene expression, are not ful...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534668/ https://www.ncbi.nlm.nih.gov/pubmed/31127120 http://dx.doi.org/10.1038/s41467-019-10318-6 |