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Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration

Clinical research has shown that chronic antipsychotic drug (APD) treatment further decreases cortical gray matter and hippocampus volume, and increases striatal and ventricular volume in patients with schizophrenia. D2-like receptor blockade is necessary for clinical efficacy of the drugs, and may...

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Detalles Bibliográficos
Autores principales: Guma, Elisa, Rocchetti, Jill, Devenyi, Gabriel A., Tanti, Arnaud, Mathieu, Axel P., Lerch, Jason P., Elgbeili, Guillaume, Courcot, Blandine, Mechawar, Naguib, Chakravarty, M. Mallar, Giros, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534671/
https://www.ncbi.nlm.nih.gov/pubmed/31127135
http://dx.doi.org/10.1038/s41598-019-43955-4