Drug transporter and oxidative stress gene expression in human macrophages infected with benznidazole-sensitive and naturally benznidazole-resistant Trypanosoma cruzi parasites treated with benznidazole

BACKGROUND: Chagas disease is a potentially life-threatening disease caused by the protozoan parasite Trypanosoma cruzi. Current therapeutic management is limited to treatment with nitroheterocyclic drugs, such as nifurtimox (NFX) and benznidazole (BZ). Thus, the identification of affordable and rea...

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Detalles Bibliográficos
Autores principales: Téllez, Jair, Romero, Ibeth, Romanha, Alvaro José, Steindel, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534881/
https://www.ncbi.nlm.nih.gov/pubmed/31126349
http://dx.doi.org/10.1186/s13071-019-3485-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534881/
https://www.ncbi.nlm.nih.gov/pubmed/31126349
http://dx.doi.org/10.1186/s13071-019-3485-9

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