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Association between metformin use and disease progression in obese people with knee osteoarthritis: data from the Osteoarthritis Initiative—a prospective cohort study

OBJECTIVE: To examine whether metformin use was associated with knee cartilage volume loss over 4 years and risk of total knee replacement over 6 years in obese individuals with knee osteoarthritis. METHODS: This study analysed the Osteoarthritis Initiative participants with radiographic knee osteoa...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Hussain, Sultana Monira, Wluka, Anita E., Lim, Yuan Z., Abram, François, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Cicuttini, Flavia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534888/
https://www.ncbi.nlm.nih.gov/pubmed/31126352
http://dx.doi.org/10.1186/s13075-019-1915-x