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Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells

BACKGROUND: Liposarcoma (LPS) is a tumor derived from adipose tissue, and has the highest incidence among soft tissue sarcomas. Dedifferentiated liposarcoma (DDLPS) is a malignant tumor with poor prognosis. Recurrence and metastasis rates in LPS remain high even after chemotherapy and radiotherapy f...

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Detalles Bibliográficos
Autores principales: Jo, Eun Byeol, Lee, Young Sang, Lee, Hyunjoo, Park, Jae Berm, Park, Hyojun, Choi, Yoon-La, Hong, Doopyo, Kim, Sung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534902/
https://www.ncbi.nlm.nih.gov/pubmed/31126284
http://dx.doi.org/10.1186/s12885-019-5713-2