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Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine

BACKGROUND: In non-human primates (NHPs) and humans, partial protection from HIV/SIV infection or suppression of replication is achievable by Env-binding antibodies and Gag-specific CD8+ T-cells targeting protective epitopes. Unfortunately, such T-cell responses are frequently dominated by responses...

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Detalles Bibliográficos
Autores principales: Schwerdtfeger, Melanie, Andersson, Anne-Marie Carola, Neukirch, Lasse, Holst, Peter Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534914/
https://www.ncbi.nlm.nih.gov/pubmed/31126293
http://dx.doi.org/10.1186/s12967-019-1924-1