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Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine
BACKGROUND: In non-human primates (NHPs) and humans, partial protection from HIV/SIV infection or suppression of replication is achievable by Env-binding antibodies and Gag-specific CD8+ T-cells targeting protective epitopes. Unfortunately, such T-cell responses are frequently dominated by responses...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534914/ https://www.ncbi.nlm.nih.gov/pubmed/31126293 http://dx.doi.org/10.1186/s12967-019-1924-1 |