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Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs

There is a growing body of evidence linking maternal overnutrition to obesity and psychopathology that can be conserved across multiple generations. Recently, we demonstrated in a maternal high-fat diet (HFD; MHFD) mouse model that MHFD induced enhanced hedonic behaviors and obesogenic phenotypes th...

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Detalles Bibliográficos
Autores principales: Sarker, Gitalee, Sun, Wenfei, Rosenkranz, David, Pelczar, Pawel, Opitz, Lennart, Efthymiou, Vissarion, Wolfrum, Christian, Peleg-Raibstein, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534971/
https://www.ncbi.nlm.nih.gov/pubmed/31061112
http://dx.doi.org/10.1073/pnas.1820810116