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Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs
There is a growing body of evidence linking maternal overnutrition to obesity and psychopathology that can be conserved across multiple generations. Recently, we demonstrated in a maternal high-fat diet (HFD; MHFD) mouse model that MHFD induced enhanced hedonic behaviors and obesogenic phenotypes th...
Autores principales: | Sarker, Gitalee, Sun, Wenfei, Rosenkranz, David, Pelczar, Pawel, Opitz, Lennart, Efthymiou, Vissarion, Wolfrum, Christian, Peleg-Raibstein, Daria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534971/ https://www.ncbi.nlm.nih.gov/pubmed/31061112 http://dx.doi.org/10.1073/pnas.1820810116 |
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