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RNA ligands activate the Machupo virus polymerase and guide promoter usage
Segmented negative-sense (SNS) RNA viruses initiate infection by delivering into cells a suite of genomic RNA segments, each sheathed by the viral nucleocapsid protein and bound by the RNA-dependent RNA-polymerase (RdRP). For the orthomyxovirus influenza and the bunyavirus La Crosse, the 5′ end of t...
Autores principales: | Pyle, Jesse D., Whelan, Sean P. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535001/ https://www.ncbi.nlm.nih.gov/pubmed/31072925 http://dx.doi.org/10.1073/pnas.1900790116 |
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