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Effects of α-tubulin acetylation on microtubule structure and stability

Acetylation of K40 in α-tubulin is the sole posttranslational modification to mark the luminal surface of microtubules. It is still controversial whether its relationship with microtubule stabilization is correlative or causative. We have obtained high-resolution cryo-electron microscopy (cryo-EM) r...

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Detalles Bibliográficos
Autores principales: Eshun-Wilson, Lisa, Zhang, Rui, Portran, Didier, Nachury, Maxence V., Toso, Daniel B., Löhr, Thomas, Vendruscolo, Michele, Bonomi, Massimiliano, Fraser, James S., Nogales, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535015/
https://www.ncbi.nlm.nih.gov/pubmed/31072936
http://dx.doi.org/10.1073/pnas.1900441116