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Five miRNAs-mediated PIEZO2 downregulation, accompanied with activation of Hedgehog signaling pathway, predicts poor prognosis of breast cancer

Roles of Piezo-type mechanosensitive ion channel component 2 (PIEZO2) in cancer remain largely unknown. Herein, we explored PIEZO2 expression, prognosis and underlying mechanisms in cancer. Breast was selected as the candidate as its relatively higher expression level of PIEZO2 than other human tiss...

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Detalles Bibliográficos
Autores principales: Lou, Weiyang, Liu, Jingxing, Ding, Bisha, Jin, Luqi, Xu, Liang, Li, Xia, Chen, Jing, Fan, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535055/
https://www.ncbi.nlm.nih.gov/pubmed/31058608
http://dx.doi.org/10.18632/aging.101934