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Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice
The activation of transcription factor NF-κB is currently identified as one of the driving forces to the aging process. Genetic impairment of NF-κB signaling pathway or pharmacological inhibition of NF-κB activity has been shown to extend healthspan and lifespan in animal models, and delay or reduce...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535057/ https://www.ncbi.nlm.nih.gov/pubmed/31048563 http://dx.doi.org/10.18632/aging.101932 |