Modulation of Coenzyme Q(10) content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging

Coenzyme Q(10) (CoQ(10)) is an endogenous lipophilic quinone, ubiquitous in biological membranes and endowed with antioxidant and bioenergetic properties, both crucial to the aging process. In fact, coenzyme Q(10) synthesis is known to decrease with age in different tissues including skin. Moreover,...

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Detalles Bibliográficos
Autores principales: Marcheggiani, Fabio, Cirilli, Ilenia, Orlando, Patrick, Silvestri, Sonia, Vogelsang, Alexandra, Knott, Anja, Blatt, Thomas, Weise, Julia M., Tiano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535058/
https://www.ncbi.nlm.nih.gov/pubmed/31076563
http://dx.doi.org/10.18632/aging.101926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535058/
https://www.ncbi.nlm.nih.gov/pubmed/31076563
http://dx.doi.org/10.18632/aging.101926

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