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Phloretin protects against cardiac damage and remodeling via restoring SIRT1 and anti-inflammatory effects in the streptozotocin-induced diabetic mouse model

Diabetic cardiomyopathy increases the risk of heart failure independent of coronary artery disease and hypertension. Phloretin (PHL) shows anti-inflammatory effects in macrophages. In this study, we explored the protective effects of PHL on high glucose (HG)-induced injury in diabetic cardiomyopathy...

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Detalles Bibliográficos
Autores principales: Ying, Yin, Jiang, Cheng, Zhang, Meiling, Jin, Jiye, Ge, Shuyu, Wang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535073/
https://www.ncbi.nlm.nih.gov/pubmed/31076562
http://dx.doi.org/10.18632/aging.101954