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Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-ĸB pathway in chondrocytes

Platelet lysate (PL) contains a cocktail of growth factors that actively participates in cartilage repair. This study was designed to determine the effect and mechanism of PL on osteoarthritis (OA). An arthritis model was established to mimic human OA by intra-articular injection of monoiodoacetate...

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Detalles Bibliográficos
Autores principales: Yan, Li, Zhou, Li, Xie, Danting, Du, Wenxi, Chen, Fangming, Yuan, Qiang, Tong, Peijian, Shan, Letian, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535074/
https://www.ncbi.nlm.nih.gov/pubmed/31089001
http://dx.doi.org/10.18632/aging.101952