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Downregulation of miR-125b promotes resistance of glioma cells to TRAIL through overexpression of Tafazzin which is a mitochondrial protein

Overexpression of Tafazzin (TAZ), a mitochondrial protein, is often observed in many cancers. However, the association between aberrant expression of TAZ and drug resistance remains unclear. The aim of this study is to explore the role of TAZ in regulating the TRAIL resistance in glioma. We thus est...

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Detalles Bibliográficos
Autores principales: Ma, Wenjia, Cui, Yan, Liu, Min, Tan, Zhigang, Jiang, Yugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535077/
https://www.ncbi.nlm.nih.gov/pubmed/31056533
http://dx.doi.org/10.18632/aging.101939